It is also the most important risk factor for neurodegenerative disorders, particularly Alzheimer’s disease (AD). To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.Īging is often associated with a cognitive decline and a susceptibility to neuronal damage. PDF is the official format for papers published in both, html and pdf forms.You may sign up for e-mail alerts to receive table of contents of newly released issues.Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.Here, we review representative bioinformatics methods published in the past five years to define major current approaches to the understanding of AMR mechanisms, prediction of AMR, and the potential for clinical application. New high-throughput technologies have enabled unbiased insights into the functional genomics of pathogens and their strategies to counter the action of antimicrobials. The search both for more efficient treatments and for new classes of antibiotics requires a better understanding of the underlying molecular mechanisms of pathogenesis and AMR. Antimicrobial resistance (AMR) is a major health concern worldwide.
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